ABSTRACT
Non-invasive ventilation (NIV) can be used in acute hypoxemic respiratory failure (AHRF); however, verifying the best interface for its use needs to be evaluated in the COVID-19 pandemic scenario. To evaluate the behavior of the PaO2/FiO2 ratio in patients with AHRF with and without COVID-19 undergoing NIV with the conventional orofacial mask and the adapted diving mask. This is a randomized clinical trial in which patients were allocated into four groups: Group 1: COVID-19 + adapted mask (n=12); Group 2: COVID-19 + conventional orofacial mask (n=12); Group 3: non-COVID + adapted mask (n= 2); and Group 4: non-COVID + conventional orofacial mask (n=12]. The PaO2/FiO2 ratio was obtained 1, 24 and 48 h after starting NIV and the success of NIV was evaluated. This study followed the norms of the CONSORT Statement and registered in the Brazilian Registry of Clinical Trials, under registration RBR - 7xmbgsz. Both the adapted diving mask and the conventional orofacial mask increased the PaO2/FiO2 ratio. The interfaces differed in terms of the PaO2/FiO2 ratio in the first hour [309.66 (11.48) and 275.71 (11.48), respectively] (p=0.042) and 48 h [365.81 (16.85) and 308.79 (18.86), respectively] (p=0.021). NIV success was 91.7% in groups 1, 2 and 3, and 83.3% in Group 4. No adverse effects related to interfaces or NIV were observed. NIV through the conventional orofacial mask interfaces and the adapted diving mask was effective in improving the PaO2/FiO2 ratio, however, the adapted mask presented a better PaO2/FiO2 ratio during use. There was no significant difference between interfaces regarding NIV failure.
ABSTRACT
Abstract Introduction Remote teaching during the COVID-19 pandemic caused teachers to work under adverse conditions and sit in front of a computer rather than stand, which can lead to musculoskeletal pain and stress in this population. Objective To observe the prevalence of musculoskeletal pain and its correlation with stress levels in teachers during the remote teaching period of the COVID-19 pandemic. Methods A cross-sectional study carried out in elementary and high schools in the city of São José do Belmonte, Pernambuco state (PE). Sixty teachers of both sexes aged 18 years and older were evaluated. The Nordic Questionnaire of Musculoskeletal Symptoms (NQMS) was used to assess musculoskeletal pain, the Visual Analogue Scale to quantify pain intensity and the Maslach Burnout Inventory to identify symptoms of stress and burnout. Results Seventy five percent (n = 45) of the teachers reported musculoskeletal pain, with a higher prevalence in the lumbar spine 68.3% (n = 41), followed by the cervical spine 45.0% (n = 27),thoracic spine, wrists and hands, both with 41.7% (n = 25). A positive correlation was observed between the presence of musculoskeletal pain and high levels of occupational stress (p = 0.036). Conclusion A high prevalence of musculoskeletal pain was identified in teachers during the remote teaching period. The lumbar, cervical and thoracic spine, wrists and hands exhibited the highest pain prevalence. Teachers who experienced musculoskeletal pain had higher stress levels and there was a positive correlation between musculoskeletal pain intensity and high occupational stress levels.
Resumo Introdução O ensino remoto, ocorrido durante a pan-demia de COVID-19, levou os professores a trabalharem em condições adversas e modificou a postura em que eles ensinavam, passando da posição ortostática para a sentada diante de um computador, o que pode favorecer a presença de dores musculoesqueléticas e estresse. Objetivo Observar a prevalência de dor musculoesquelética e sua correlação com níveis de estresse em professores durante o ensino remoto na pandemia de COVID-19. Métodos Estudo de corte transversal realizado em escolas do ensino fundamental e médio do município de São José do Belmonte, em Pernambuco. Foram avaliados 60 professores, de ambos os sexos e faixa etária acima dos 18 anos. Para avaliar a presença de dores musculoesqueléticas, utilizou-se o N ordic Questionnaire of Musculoskeletal Symptoms ; para quantificar a intensidade das dores, a Escala Visual Analógica; e para identificar sintomas de estresse e esgotamento profissional, o Maslach Burnout Inventory . Resultados Setenta e cinco por cento (n = 45) dos professores avaliados apresentavam dores musculo-esqueléticas, com maior prevalência na coluna lombar (68,3%, n = 41), seguida pela coluna cervical (45,0%,n = 27), coluna torácica, punhos e mãos, ambos com (41,7%, n = 25). Observou-se também uma correlação positiva entre a presença de dor musculoesquelética e níveis elevados de estresse ocupacional nos professores avaliados (p = 0,036). Conclusão Observou-se uma elevada prevalência de dor musculoesquelética nos professores durante o período de ensino remoto. A coluna lombar, cervical, torácica, punhos e mãos foram as regiões com maior prevalência das dores. Os professores que apresentavam dor musculoesquelética relataram maiores níveis de estresse e houve uma correlação positiva entre a intensidade da dor musculoesquelética e níveis elevados de estresse ocupacional.
ABSTRACT
Objective: To investigate vascular and perivascular abnormalities in the carotid arteries using ultrasound, as well as to evaluate their association with mortality and clinical variables in hospitalized patients with coronavirus disease 2019 (COVID-19). Materials and Methods: This was a prospective study in which 53 hospitalized patients with severe COVID-19 were evaluated and underwent carotid ultrasound. We documented the carotid ultrasound findings in these patients. Clinical, demographic, laboratory, and imaging features were analyzed and compared by statistical analysis to detect correlations between them. Results: Carotid ultrasound demonstrated luminal surface irregularity in 29 patients (55%), carotid plaques in 30 (57%), perivascular infiltration in four (8%), and increased intima-media thickness (IMT) in 31 (58%). Of the 31 patients with increased IMT, 19 (61%) died, and the association between increased IMT and COVID-19-related mortality was significant (p = 0.03). Logistic regression showed that the risk of death was 85% in patients who had increased IMT in combination with acute kidney injury at admission or a history of chronic kidney disease (p < 0.05). Conclusion: In hospitalized patients with severe COVID-19, carotid ultrasound can show increased IMT, luminal surface irregularity, carotid plaques, and perivascular infiltrates. The combination of increased IMT and kidney damage appears to increase the risk of death in such patients.
Objetivo: Investigar anormalidades vasculares e perivasculares nas artérias carótidas por meio de ultrassonografia e avaliar sua associação com mortalidade e variáveis clínicas em pacientes hospitalizados com COVID-19. Materiais e Métodos: Neste estudo prospectivo, 53 pacientes hospitalizados com COVID-19 grave foram avaliados e submetidos a ultrassonografia de carótida. Descrevemos os achados ultrassonográficos de carótida nesses pacientes. As correlações de características clínicas, demográficas, laboratoriais e de imagem foram analisadas e comparadas por meio de análise estatística. Resultados: A ultrassonografia carotídea demonstrou irregularidade da superfície luminal em 29 pacientes (55%), placas carotídeas em 30 pacientes (57%), infiltração perivascular em quatro pacientes (7,5%) e aumento da espessura médio-intimal (EMI) em 31 pacientes (58%). Dos pacientes com EMI aumentada, 19 (61%) morreram, com associação observada entre EMI aumentada e mortalidade por COVID-19 (p = 0,03). Um modelo de regressão logística mostrou que a probabilidade de óbito foi de 85% em pacientes com EMI aumentada e história de nefropatia crônica ou lesão renal aguda na internação (p < 0,05). Conclusão: Aumento da EMI, irregularidade da superfície luminal, placas carotídeas e infiltrados perivasculares foram encontrados na ultrassonografia carotídea em pacientes hospitalizados com COVID-19 grave. O aumento da EMI associado a danos nos rins pode aumentar o risco de morte.